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The Phase 3 TRIUMPH-4 trial, announced by Eli Lilly, delivered even more dramatic results

Meanwhile, the combination of an A2A receptor antagonist and mGluR5 antagonist also promotes neuroprotection and activates the indirect corticostriatal circuit while reducing PD-like symptoms

PMID: 31436480

Common GI side effects like nausea, diarrhea, and abdominal pain tend to be mild and manageable

The two-and-a-half-hour performance contains a staggering 20,000 words, four times more than the average musical, at times whizzing by at a pace of six words per second, and the music has an ultra-modern, in-your-face, hip-hop/R&B feel